Quantitative Method for Evaluating Test Results
نویسندگان
چکیده
منابع مشابه
A quantitative method for evaluating the stabilities of nucleic acids.
We report a general method for screening, in solution, the impact of deviations from canonical Watson-Crick composition on the thermodynamic stability of nucleic acid duplexes. We demonstrate how fluorescence resonance energy transfer (FRET) can be used to detect directly free energy differences between an initially formed "reference" duplex (usually a Watson-Crick duplex) and a related "test" ...
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ژورنال
عنوان ژورنال: Vestnik NSUEM
سال: 2020
ISSN: 2073-6495
DOI: 10.34020/2073-6495-2020-3-144-154